Pathogenesis of Neonatal Herpes Simplex 2 Disease in a Mouse Model Is Dependent on Entry Receptor Expression and Route of Inoculation

Herpes simplex virus (HSV) pathogenesis in mice differs based on availability of the principal entry receptors herpesvirus entry mediator (HVEM) and nectin-1 in a manner dependent upon route of inoculation. After intravaginal or intracranial inoculation of adult mice, nectin-1 is a major mediator of...

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Hlavní autoři: Kopp, Sarah J., Karaba, Andrew H., Cohen, Laura K., Banisadr, Ghazal, Miller, Richard J., Muller, William J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536411/
https://ncbi.nlm.nih.gov/pubmed/23097453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01849-12
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