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Herpesvirus entry mediator is a serotype specific determinant of pathogenesis in ocular herpes

Infection with herpes simplex virus type 1 (HSV-1) and HSV-2 is initiated by viral glycoprotein D (gD) binding to a receptor on the host cell. Two receptors, herpesvirus entry mediator (HVEM) and nectin-1, mediate entry in murine models of HSV-1 and HSV-2. HVEM is dispensable for HSV-2 infection of...

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Detalhes bibliográficos
Main Authors: Karaba, Andrew H., Kopp, Sarah J., Longnecker, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528501/
https://ncbi.nlm.nih.gov/pubmed/23184983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216967109
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