Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice

RATIONALE: Previous studies indicate that psychosocial stressors could accelerate amyloid-β (Aβ) levels and accelerate plaque deposition in mouse models of Alzheimer disease (AD). Stressors enhanced the release of corticotrophin-releasing factor (CRF) and exogenous CRF administration mimicked the ef...

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Publicat a:Psychopharmacology (Berl)
Autors principals: Dong, Hongxin, Wang, Shirlene, Zeng, Ziling, Li, Fei, Montalvo-Ortiz, Janitza, Tucker, Christopher, Akhtar, Shahzad, Shi, Jingshan, Meltzer, Herbert Y., Rice, Kenner C., Csernansky, John G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233002/
https://ncbi.nlm.nih.gov/pubmed/24862368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3629-8
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