Corticotrophin releasing factor receptor 1antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats

Mounting evidence suggests that chronic stress can alter brain structure and function and promote the development of neuropsychiatric disorders, such as depression and Alzheimer’s disease. Although the results of several studies have indicated that aged brains are more vulnerable to chronic stress,...

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Bibliographic Details
Published in:Psychoneuroendocrinology
Main Authors: Dong, Hongxin, Keegan, Jack M, Hong, Ellie, Gallardo, Christopher, Montalvo-Ortiz, Janitza, Wang, Becky, Rice, Kenner C., Csernansky, John
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864558/
https://ncbi.nlm.nih.gov/pubmed/29477954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2018.02.013
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