A central role for Notch in effector CD8(+) T cell differentiation

Activated CD8(+) T cells choose between terminal effector cell (TEC) or memory precursor cell (MPC) fates. We show that Notch controls this choice. Notch promoted differentiation of immediately protective TECs and was correspondingly required for clearance of an acute influenza virus infection. Notc...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Nat Immunol
Main Authors: Backer, Ronald A., Helbig, Christina, Gentek, Rebecca, Kent, Andrew, Laidlaw, Brian J., Dominguez, Claudia X., de Souza, Yevan S., van Trierum, Stella E., van Beek, Ruud, Rimmelzwaan, Guus F., ten Brinke, Anja, Willemsen, A. Marcel, van Kampen, Antoine H. C., Kaech, Susan M., Blander, J. Magarian, van Gisbergen, Klaas, Amsen, Derk
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232996/
https://ncbi.nlm.nih.gov/pubmed/25344724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3027
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla