Neuropathology of the Mcoln1(−/−) Knockout Mouse Model of Mucolipidosis Type IV

The recently developed Mcoln1(−/−) knockout mouse provides a novel model for analyzing mucolipin 1 (TRP-ML1) function and mucolipidosis type IV (MLIV) disease. Here we characterize the neuropathology of the Mcoln1(−/−) mouse at the end stage. Evidence of ganglioside accumulation, including increases...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neuropathol Exp Neurol
Prif Awduron: Micsenyi, Matthew C., Dobrenis, Kostantin, Stephney, Gloria, Pickel, James, Vanier, Marie T., Slaugenhaupt, Susan A., Walkley, Steven U.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232971/
https://ncbi.nlm.nih.gov/pubmed/19151629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181942cf0
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg