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Neuropathology of the Mcoln1(−/−) Knockout Mouse Model of Mucolipidosis Type IV
The recently developed Mcoln1(−/−) knockout mouse provides a novel model for analyzing mucolipin 1 (TRP-ML1) function and mucolipidosis type IV (MLIV) disease. Here we characterize the neuropathology of the Mcoln1(−/−) mouse at the end stage. Evidence of ganglioside accumulation, including increases...
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| Vydáno v: | J Neuropathol Exp Neurol |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4232971/ https://ncbi.nlm.nih.gov/pubmed/19151629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181942cf0 |
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