Reconstitution of a minimal mtDNA replisome in vitro
We here reconstitute a minimal mammalian mitochondrial DNA (mtDNA) replisome in vitro. The mtDNA polymerase (POLγ) cannot use double-stranded DNA (dsDNA) as template for DNA synthesis. Similarly, the TWINKLE DNA helicase is unable to unwind longer stretches of dsDNA. In combination, POLγ and TWINKLE...
Tallennettuna:
| Julkaisussa: | EMBO J |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2004
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423294/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15167897/ https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600257 |
| Tagit: |
Ei tageja, Lisää ensimmäinen tagi!
|