CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection

Costimulation of purified CD8(+) T lymphocytes induces de novo expression of CD4, suggesting a previously unrecognized function for this molecule in the immune response. Here, we report that the CD4 molecule plays a direct role in CD8(+) T cell function by modulating expression of IFN-γ and Fas liga...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Kitchen, Scott G., Jones, Nicole R., LaForge, Stuart, Whitmire, Jason K., Vu, Bien-Aimee, Galic, Zoran, Brooks, David G., Brown, Stephen J., Kitchen, Christina M. R., Zack, Jerome A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC423263/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15173593/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401500101
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak