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CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection
Costimulation of purified CD8(+) T lymphocytes induces de novo expression of CD4, suggesting a previously unrecognized function for this molecule in the immune response. Here, we report that the CD4 molecule plays a direct role in CD8(+) T cell function by modulating expression of IFN-γ and Fas liga...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2004
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC423263/ https://ncbi.nlm.nih.gov/pubmed/15173593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401500101 |
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