Inhibition of cardiac Kv1.5 potassium current by the anesthetic midazolam: mode of action

Midazolam is a short-acting benzodiazepine that is widely used in anesthesia. Despite its widespread clinical use, detailed information about cardiac side effects of midazolam is largely lacking. Using the double-electrode voltage clamp technique, we studied pharmacological effects of midazolam on h...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Vonderlin, Nadine, Fischer, Fathima, Zitron, Edgar, Seyler, Claudia, Scherer, Daniel, Thomas, Dierk, Katus, Hugo A, Scholz, Eberhard P
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232042/
https://ncbi.nlm.nih.gov/pubmed/25422586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S70461
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