Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase

Basic fibroblast growth factor 2 (bFGF) is a potent mitogen for mesenchymal cells, and the local application of recombinant bFGF accelerates bone union and defect repair. However, repeated dosing is required for sustained therapeutic effect as the efficacy of bFGF decreases rapidly following its dif...

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Bibliografiske detaljer
Udgivet i:J Biomed Mater Res A
Main Authors: Uchida, Kentaro, Matsushita, Osamu, Naruse, Kouji, Mima, Takehiko, Nishi, Nozomu, Hattori, Shunji, Ogura, Takayuki, Inoue, Gen, Tanaka, Keisuke, Takaso, Masashi
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2014
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232007/
https://ncbi.nlm.nih.gov/pubmed/23775724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.34841
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