Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase

Basic fibroblast growth factor 2 (bFGF) is a potent mitogen for mesenchymal cells, and the local application of recombinant bFGF accelerates bone union and defect repair. However, repeated dosing is required for sustained therapeutic effect as the efficacy of bFGF decreases rapidly following its dif...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Uchida, Kentaro, Matsushita, Osamu, Naruse, Kouji, Mima, Takehiko, Nishi, Nozomu, Hattori, Shunji, Ogura, Takayuki, Inoue, Gen, Tanaka, Keisuke, Takaso, Masashi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232007/
https://ncbi.nlm.nih.gov/pubmed/23775724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.34841
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