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Interplay between allostery and intrinsic disorder in an ensemble

Allostery is a biological phenomenon of critical importance in metabolic regulation and cell signalling. The fundamental premise of classical models that describe allostery is that structure mediates ‘action at a distance’. Recently, this paradigm has been challenged by the enrichment of IDPs (intri...

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Pubblicato in:Biochem Soc Trans
Autori principali: Motlagh, Hesam N., Li, Jing, Thompson, E. Brad, Hilser, Vincent J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231872/
https://ncbi.nlm.nih.gov/pubmed/22988850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20120163
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