Ribosome-controlled transcription termination is essential for the production of antibiotic microcin C

Microcin C (McC) is a peptide–nucleotide antibiotic produced by Escherichia coli cells harboring a plasmid-borne operon mccABCDE. The heptapeptide MccA is converted into McC by adenylation catalyzed by the MccB enzyme. Since MccA is a substrate for MccB, a mechanism that regulates the MccA/MccB rati...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zukher, Inna, Novikova, Maria, Tikhonov, Anton, Nesterchuk, Mikhail V., Osterman, Ilya A., Djordjevic, Marko, Sergiev, Petr V., Sharma, Cynthia M., Severinov, Konstantin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231749/
https://ncbi.nlm.nih.gov/pubmed/25274735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku880
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