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ClpXP protease targets long-lived DNA translocation states of a helicase-like motor to cause restriction alleviation

We investigated how Escherichia coli ClpXP targets the helicase-nuclease (HsdR) subunit of the bacterial Type I restriction–modification enzyme EcoKI during restriction alleviation (RA). RA is a temporary reduction in endonuclease activity that occurs when Type I enzymes bind unmodified recognition...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Simons, Michelle, Diffin, Fiona M., Szczelkun, Mark D.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231737/
https://ncbi.nlm.nih.gov/pubmed/25260590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku851
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