Hu Antigen R (HuR) Is a Positive Regulator of the RNA-binding Proteins TDP-43 and FUS/TLS: IMPLICATIONS FOR AMYOTROPHIC LATERAL SCLEROSIS

Posttranscriptional gene regulation is governed by a network of RNA-binding proteins (RBPs) that interact with regulatory elements in the mRNA to modulate multiple molecular processes, including splicing, RNA transport, RNA stability, and translation. Mounting evidence indicates that there is a hier...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Lu, Liang, Zheng, Lei, Si, Ying, Luo, Wenyi, Dujardin, Gwendal, Kwan, Thaddaeus, Potochick, Nicholas R., Thompson, Sunnie R., Schneider, David A., King, Peter H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231657/
https://ncbi.nlm.nih.gov/pubmed/25239623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573246
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