BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues

MYC is one of the most frequently overexpressed oncogenes in human cancer and even modestly deregulated MYC can initiate ectopic proliferation in many post-mitotic cell types in vivo. Sensitization of cells to apoptosis limits MYC’s oncogenic potential. However, the mechanism through which MYC induc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Muthalagu, Nathiya, Junttila, Melissa, Wiese, Katrin E., Wolf, Elmar, Morton, Jennifer, Bauer, Barbara, Evan, Gerard I., Eilers, Martin, Murphy, Daniel J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231288/
https://ncbi.nlm.nih.gov/pubmed/25176652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.057
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