Independent oncogenic and therapeutic significance of phosphatase PRL-3 in FLT3-ITD–negative acute myeloid leukemia

BACKGROUND: Internal tandem duplication of FMS-like tyrosine kinase (FLT3-ITD) is well known to be involved in acute myeloid leukemia (AML) progression, but FLT3-ITD–negative AML cases account for 70% to 80% of AML, and the mechanisms underlying their pathology remain unclear. This study identifies...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer
Päätekijät: Qu, Shuang, Liu, Bin, Guo, Xiaoling, Shi, Hongshun, Zhou, Meifeng, Li, Li, Yang, Shulan, Tong, Xiuzhen, Wang, Haihe
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BlackWell Publishing Ltd 2014
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Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231236/
https://ncbi.nlm.nih.gov/pubmed/24737397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28668
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