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Gait Analysis in a Mecp2 Knockout Mouse Model of Rett Syndrome Reveals Early-Onset and Progressive Motor Deficits

Rett syndrome (RTT) is a genetic disorder characterized by a range of features including cognitive impairment, gait abnormalities and a reduction in purposeful hand skills. Mice harbouring knockout mutations in the Mecp2 gene display many RTT-like characteristics and are central to efforts to find n...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gadalla, Kamal K. E., Ross, Paul D., Riddell, John S., Bailey, Mark E. S., Cobb, Stuart R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231076/
https://ncbi.nlm.nih.gov/pubmed/25392929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112889
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