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MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats

Since the identification of MECP2 as the causative gene in the majority of Rett Syndrome (RTT) cases, transgenic mouse models have played a critical role in our understanding of this disease. The use of additional mammalian RTT models offers the promise of further elucidating critical early mechanis...

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Bibliografische gegevens
Gepubliceerd in:Hum Mol Genet
Hoofdauteurs: Patterson, Kelsey C., Hawkins, Virginia E., Arps, Kara M., Mulkey, Daniel K., Olsen, Michelle L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179928/
https://ncbi.nlm.nih.gov/pubmed/27329765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw179
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