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MeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female rats

Since the identification of MECP2 as the causative gene in the majority of Rett Syndrome (RTT) cases, transgenic mouse models have played a critical role in our understanding of this disease. The use of additional mammalian RTT models offers the promise of further elucidating critical early mechanis...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Patterson, Kelsey C., Hawkins, Virginia E., Arps, Kara M., Mulkey, Daniel K., Olsen, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179928/
https://ncbi.nlm.nih.gov/pubmed/27329765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw179
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