Predictive Value of Interferon-Lambda Gene Polymorphisms for Treatment Response in Chronic Hepatitis C

BACKGROUND: IL28B gene polymorphism is the best baseline predictor of response to interferon alfa-based antiviral therapies in chronic hepatitis C. Recently, a new IFN-L4 polymorphism was identified as first potential functional variant for induction of IL28B expression. Individualization of interfe...

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Vydáno v:PLoS One
Hlavní autoři: Susser, Simone, Herrmann, Eva, Lange, Christian, Hamdi, Nabila, Müller, Tobias, Berg, Thomas, Perner, Dany, Zeuzem, Stefan, Sarrazin, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231027/
https://ncbi.nlm.nih.gov/pubmed/25393304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112592
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