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Hepatitis C Virus Nonstructural 5A Protein and Interferon Resistance: a New Model for Testing the Reliability of Mutational Analyses

Presumably due to the capability of the hepatitis C virus (HCV) to evade the antiviral effects of alpha interferon, treatment is ineffective in more than half of chronically genotype HCV type 1 (HCV-1)-infected patients. Previous approaches to correlate the number of amino acid mutations within regi...

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Bibliografiske detaljer
Main Authors: Sarrazin, Christoph, Herrmann, Eva, Bruch, Katharina, Zeuzem, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136596/
https://ncbi.nlm.nih.gov/pubmed/12368350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.11079-11090.2002
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