Genetic Analysis of a Novel Tubulin Mutation That Redirects Synaptic Vesicle Targeting and Causes Neurite Degeneration in C. elegans

Neuronal cargos are differentially targeted to either axons or dendrites, and this polarized cargo targeting critically depends on the interaction between microtubules and molecular motors. From a forward mutagenesis screen, we identified a gain-of-function mutation in the C. elegans α-tubulin gene...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Hsu, Jiun-Min, Chen, Chun-Hao, Chen, Yen-Chih, McDonald, Kent L., Gurling, Mark, Lee, Albert, Garriga, Gian, Pan, Chun-Liang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230729/
https://ncbi.nlm.nih.gov/pubmed/25392990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004715
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller