Tomosyn Inhibits Synaptic Vesicle Priming in Caenorhabditis elegans

Caenorhabditis elegans TOM-1 is orthologous to vertebrate tomosyn, a cytosolic syntaxin-binding protein implicated in the modulation of both constitutive and regulated exocytosis. To investigate how TOM-1 regulates exocytosis of synaptic vesicles in vivo, we analyzed C. elegans tom-1 mutants. Our el...

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Main Authors: Gracheva, Elena O, Burdina, Anna O, Holgado, Andrea M, Berthelot-Grosjean, Martine, Ackley, Brian D, Hadwiger, Gayla, Nonet, Michael L, Weimer, Robby M, Richmond, Janet E
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2006
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1514790/
https://ncbi.nlm.nih.gov/pubmed/16895441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040261
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