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Polylysine-Mediated Translocation of the Diphtheria Toxin Catalytic Domain through the Anthrax Protective Antigen Pore

[Image: see text] The protective antigen (PA) moiety of anthrax toxin forms oligomeric pores in the endosomal membrane, which translocate the effector proteins of the toxin to the cytosol. Effector proteins bind to oligomeric PA via their respective N-terminal domains and undergo N- to C-terminal tr...

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Bibliografiske detaljer
Udgivet i:Biochemistry
Main Authors: Sharma, Onkar, Collier, R. John
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230326/
https://ncbi.nlm.nih.gov/pubmed/25317832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500985v
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