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Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer
BACKGROUND: Family history of prostate cancer is a well-recognized risk factor. Previous linkage studies have reported a putative prostate cancer susceptibility locus at chromosome 17q21-22. SPOP (Speckle-type POZ protein)maps to the 17q21-22 candidate linkage region and is one of the most frequentl...
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| Vydáno v: | Prostate |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4230298/ https://ncbi.nlm.nih.gov/pubmed/24796539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22818 |
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