Absence of truncating BRIP1 mutations in chromosome 17q-linked hereditary prostate cancer families

BACKGROUND: In a genome-wide scan (GWS) of 175 multiplex prostate cancer (PCa) families from the University of Michigan Prostate Cancer Genetics Project (PCGP), linkage was observed to markers on chromosome 17q21–24, a region that includes two breast cancer susceptibility genes, BRCA1 and BRIP1. BRI...

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Detalhes bibliográficos
Main Authors: Ray, A M, Zuhlke, K A, Johnson, G R, Levin, A M, Douglas, J A, Lange, E M, Cooney, K A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795448/
https://ncbi.nlm.nih.gov/pubmed/19935797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605433
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