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Chromosome 17q12 variants contribute to risk of early-onset prostate cancer

In a recent genome-wide association study by Gudmundsson et al. (2007), two prostate cancer susceptibility loci were identified on chromosome 17q. The first locus, at 17q12, was distinguished by two intronic single nucleotide polymorphisms (SNPs) in the TCF2 gene (rs4430796 and rs7501939). The secon...

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Detalhes bibliográficos
Main Authors: Levin, Albert M., Machiela, Mitchell J., Zuhlke, Kimberly A., Ray, Anna M., Cooney, Kathleen A., Douglas, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2562290/
https://ncbi.nlm.nih.gov/pubmed/18701471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-0348
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