MiR-378 overexpression attenuates high glucose-suppressed osteogenic differentiation through targeting CASP3 and activating PI3K/Akt signaling pathway

Hyperglycemia is one of the possible causes for osteoporosis and bone fracture in diabetes mellitus. Here we modeled diabetes-induced osteoporosis in vitro using preosteoblastic cell line MC3T3-E1 and a diabetic mice model for in vivo studies. We found that in addition to reducing osteoblast viabili...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: You, Li, Gu, Wensha, Chen, Lin, Pan, Ling, Chen, Jinyu, Peng, Yongde
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230144/
https://ncbi.nlm.nih.gov/pubmed/25400823
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados