DEVELOPMENT OF EFFECTIVE VACCINES FOR OLD MICE IN A TUMOR MODEL

Vaccines are often inefficient in old people and old mice. Few studies have focused on testing vaccines in old populations. Here we used DNA tumor antigen vaccines against melanoma and showed that old mice were not protected. Vaccines incorporating fusions of the tumor antigen with microbial adjuvan...

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Publicat a:Vaccine
Autors principals: Posnett, David N, Engelhorn, Manuel E., Lin, Yun, Merghoub, Taha, Duan, Fei, Wolchok, Jedd D, Houghton, Alan N
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229949/
https://ncbi.nlm.nih.gov/pubmed/19103244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.11.112
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