DEVELOPMENT OF EFFECTIVE VACCINES FOR OLD MICE IN A TUMOR MODEL

Vaccines are often inefficient in old people and old mice. Few studies have focused on testing vaccines in old populations. Here we used DNA tumor antigen vaccines against melanoma and showed that old mice were not protected. Vaccines incorporating fusions of the tumor antigen with microbial adjuvan...

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Veröffentlicht in:Vaccine
Hauptverfasser: Posnett, David N, Engelhorn, Manuel E., Lin, Yun, Merghoub, Taha, Duan, Fei, Wolchok, Jedd D, Houghton, Alan N
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229949/
https://ncbi.nlm.nih.gov/pubmed/19103244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.11.112
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