Mutated K65R recombinant reverse transcriptase of human immunodeficiency virus type 1 shows diminished chain termination in the presence of 2',3'-dideoxycytidine 5'-triphosphate and other drugs.

Lignende værker

• Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2',3'-dideoxycytidine and 2',3'-dideoxy-3'-thiacytidine.
  af: Gu, Z, et al.
  Udgivet: (1994)
• Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2',3'-dideoxyinosine and 2',3'-dideoxycytidine.
  af: Gu, Z, et al.
  Udgivet: (1992)
• Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase.
  af: Zhang, D, et al.
  Udgivet: (1994)
• The M184V Mutation in the Reverse Transcriptase of Human Immunodeficiency Virus Type 1 Impairs Rescue of Chain-Terminated DNA Synthesis
  af: Götte, Matthias, et al.
  Udgivet: (2000)
• The Triphosphate of β-D-4’-C-Ethynyl-2’,3’-Dideoxycytidine is the Preferred Enantiomer Substrate for HIV Reverse Transcriptase
  af: Siddiqui, Maqbool A., et al.
  Udgivet: (2006)