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Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.

Hepatitis C virus (HCV) establishes a persistent infection in humans and chimpanzees despite the presence of virus-specific, class I major histocompatibility complex-restricted CD8+ cytotoxic T lymphocytes (CTLs) in the liver. The data presented here demonstrate that CTLs directed against a conserve...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Weiner, A, Erickson, A L, Kansopon, J, Crawford, K, Muchmore, E, Hughes, A L, Houghton, M, Walker, C M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42297/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7708719/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.7.2755
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