Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.

Hepatitis C virus (HCV) establishes a persistent infection in humans and chimpanzees despite the presence of virus-specific, class I major histocompatibility complex-restricted CD8+ cytotoxic T lymphocytes (CTLs) in the liver. The data presented here demonstrate that CTLs directed against a conserve...

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Detalhes bibliográficos
Main Authors: Weiner, A, Erickson, A L, Kansopon, J, Crawford, K, Muchmore, E, Hughes, A L, Houghton, M, Walker, C M
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42297/
https://ncbi.nlm.nih.gov/pubmed/7708719
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