Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8(+) and CD4(+) T lymphocytes

Highly active antiretroviral therapy (HAART) has been advocated for the management of primary HIV-1 infection without clear understanding of its immunological effects. Here, we demonstrate that early use of HAART during primary infection preserves HIV-specific CD8(+) T cells physically and functiona...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Oxenius, Annette, Price, David A., Easterbrook, Philippa J., O'Callaghan, Christopher A., Kelleher, Anthony D., Whelan, Joseph A., Sontag, Glenn, Sewell, Andrew K., Phillips, Rodney E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737796/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.7.3382
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