Plk4 Phosphorylates Ana2 to Trigger Sas6 Recruitment and Procentriole Formation

Centrioles are 9-fold symmetrical structures at the core of centrosomes and base of cilia whose dysfunction has been linked to a wide range of inherited diseases and cancer [1]. Their duplication is regulated by a protein kinase of conserved structure, the C. elegans ZYG-1 or its Polo-like kinase 4...

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Pubblicato in:Curr Biol
Autori principali: Dzhindzhev, Nikola S., Tzolovsky, George, Lipinszki, Zoltan, Schneider, Sandra, Lattao, Ramona, Fu, Jingyan, Debski, Janusz, Dadlez, Michal, Glover, David M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4229625/
https://ncbi.nlm.nih.gov/pubmed/25264260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2014.08.061
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