Genomic amplification of MYC as double minutes in a patient with APL-like leukemia

BACKGROUND: Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML) characterized by a PML-RARA fusion due to a translocation t(15;17). Its sensitivity to treatment with all-trans retinoic acid (ATRA), which causes differentiation of the abnormal promyelocytes, combined with...

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Detalhes bibliográficos
Publicado no:Mol Cytogenet
Main Authors: Poddighe, Pino J, Wessels, Hans, Merle, Pauline, Westers, Marisa, Bhola, Shama, Loonen, Anne, Zweegman, Sonja, Ossenkoppele, Gert J, Wondergem, Marielle J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228273/
https://ncbi.nlm.nih.gov/pubmed/25392715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-014-0067-6
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