PrimPol Bypasses UV Photoproducts during Eukaryotic Chromosomal DNA Replication

DNA damage can stall the DNA replication machinery, leading to genomic instability. Thus, numerous mechanisms exist to complete genome duplication in the absence of a pristine DNA template, but identification of the enzymes involved remains incomplete. Here, we establish that Primase-Polymerase (Pri...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Bianchi, Julie, Rudd, Sean G., Jozwiakowski, Stanislaw K., Bailey, Laura J., Soura, Violetta, Taylor, Elaine, Stevanovic, Irena, Green, Andrew J., Stracker, Travis H., Lindsay, Howard D., Doherty, Aidan J.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2013
Sujets:
Short Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4228047/
https://ncbi.nlm.nih.gov/pubmed/24267451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.10.035
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