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Mycobacterium smegmatis DinB2 misincorporates deoxyribonucleotides and ribonucleotides during templated synthesis and lesion bypass

Mycobacterium smegmatis DinB2 is the founder of a clade of Y-family DNA polymerase that is naturally adept at utilizing rNTPs or dNTPs as substrates. Here we investigate the fidelity and lesion bypass capacity of DinB2. We report that DinB2 is an unfaithful DNA and RNA polymerase with a distinctive...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Ordonez, Heather, Shuman, Stewart
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227753/
https://ncbi.nlm.nih.gov/pubmed/25352547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1027
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