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Heavy transcription of yeast genes correlates with differential loss of histone H2B relative to H4 and queued RNA polymerases

Eukaryotic chromatin is composed of nucleosomes, which contain nearly two coils of DNA wrapped around a central histone octamer. The octamer contains an H3-H4 tetramer and two H2A-H2B dimers. Gene activation is associated with chromatin disruption: a wider nucleosome-depleted region (NDR) at the pro...

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Pubblicato in:Nucleic Acids Res
Autori principali: Cole, Hope A., Ocampo, Josefina, Iben, James R., Chereji, Răzvan V., Clark, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227747/
https://ncbi.nlm.nih.gov/pubmed/25348398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1013
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