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Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination

[Image: see text] We recently demonstrated that variants of cytochrome P450(BM3) (CYP102A1) catalyze the insertion of nitrogen species into benzylic C–H bonds to form new C–N bonds. An outstanding challenge in the field of C–H amination is catalyst-controlled regioselectivity. Here, we report two en...

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Bibliografische gegevens
Gepubliceerd in:J Am Chem Soc
Hoofdauteurs: Hyster, Todd K., Farwell, Christopher C., Buller, Andrew R., McIntosh, John A., Arnold, Frances H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2014
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227740/
https://ncbi.nlm.nih.gov/pubmed/25325618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja509308v
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