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Enzyme-Controlled Nitrogen-Atom Transfer Enables Regiodivergent C–H Amination

[Image: see text] We recently demonstrated that variants of cytochrome P450(BM3) (CYP102A1) catalyze the insertion of nitrogen species into benzylic C–H bonds to form new C–N bonds. An outstanding challenge in the field of C–H amination is catalyst-controlled regioselectivity. Here, we report two en...

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Bibliografiset tiedot
Julkaisussa:J Am Chem Soc
Päätekijät: Hyster, Todd K., Farwell, Christopher C., Buller, Andrew R., McIntosh, John A., Arnold, Frances H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227740/
https://ncbi.nlm.nih.gov/pubmed/25325618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja509308v
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