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Amyloid Oligomers and Protofibrils, but Not Filaments, Self-Replicate from Native Lysozyme

[Image: see text] Self-assembly of amyloid fibrils is the molecular mechanism best known for its connection with debilitating human disorders such as Alzheimer’s disease but is also associated with various functional cellular responses. There is increasing evidence that amyloid formation proceeds al...

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Опубликовано в: :J Am Chem Soc
Главные авторы: Mulaj, Mentor, Foley, Joseph, Muschol, Martin
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2014
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227717/
https://ncbi.nlm.nih.gov/pubmed/24884889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja502529m
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