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Amyloid Protofibrils of Lysozyme Nucleate and Grow Via Oligomer Fusion
The mechanisms linking deposits of insoluble amyloid fibrils to the debilitating neuronal cell death characteristic of neurodegenerative diseases remain enigmatic. Recent findings implicate transiently formed intermediates of mature amyloid fibrils as the principal toxic agent. Hence, determining wh...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711423/ https://ncbi.nlm.nih.gov/pubmed/19413984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.044 |
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