Amyloid Protofibrils of Lysozyme Nucleate and Grow Via Oligomer Fusion

The mechanisms linking deposits of insoluble amyloid fibrils to the debilitating neuronal cell death characteristic of neurodegenerative diseases remain enigmatic. Recent findings implicate transiently formed intermediates of mature amyloid fibrils as the principal toxic agent. Hence, determining wh...

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Detalles Bibliográficos
Autores principales: Hill, Shannon E., Robinson, Joshua, Matthews, Garrett, Muschol, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2009
Materias:
Supramolecular Assemblies
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711423/
https://ncbi.nlm.nih.gov/pubmed/19413984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.01.044
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