Involvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens

BACKGROUND: Cratoxylum arborescens has been used traditionally in Malaysia for the treatment of various ailments. METHODS: α-Mangostin (AM) was isolated from C. arborescens and its cell death mechanism was investigated. AM-induced cytotoxicity was observed with the 3-(4,5-dimethylthiazol-2-yl)-2,5-d...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ibrahim, Mohamed Yousif, Hashim, Najihah Mohd, Mohan, Syam, Abdulla, Mahmood Ameen, Abdelwahab, Siddig Ibrahim, Kamalidehghan, Behnam, Ghaderian, Mostafa, Dehghan, Firouzeh, Ali, Landa Zeenelabdin, Karimian, Hamed, Yahayu, Maizatulakmal, Ee, Gwendoline Cheng Lian, Farjam, Abdoreza Soleimani, Ali, Hapipah Mohd
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227646/
https://ncbi.nlm.nih.gov/pubmed/25395836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S66574
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados