Involvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens

BACKGROUND: Cratoxylum arborescens has been used traditionally in Malaysia for the treatment of various ailments. METHODS: α-Mangostin (AM) was isolated from C. arborescens and its cell death mechanism was investigated. AM-induced cytotoxicity was observed with the 3-(4,5-dimethylthiazol-2-yl)-2,5-d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Drug Des Devel Ther
मुख्य लेखकों: Ibrahim, Mohamed Yousif, Hashim, Najihah Mohd, Mohan, Syam, Abdulla, Mahmood Ameen, Abdelwahab, Siddig Ibrahim, Kamalidehghan, Behnam, Ghaderian, Mostafa, Dehghan, Firouzeh, Ali, Landa Zeenelabdin, Karimian, Hamed, Yahayu, Maizatulakmal, Ee, Gwendoline Cheng Lian, Farjam, Abdoreza Soleimani, Ali, Hapipah Mohd
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove Medical Press 2014
विषय:
Original Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227646/
https://ncbi.nlm.nih.gov/pubmed/25395836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S66574
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