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Temporal orchestration of repressive chromatin modifiers by mammalian circadian clock PERIOD complexes
The mammalian circadian clock is built on a molecular feedback loop in which the PERIOD (PER) proteins, acting in a large, poorly-understood complex, repress CLOCK-BMAL1, the transcription factor driving their expression. We found that mouse PER complexes include the histone methyltransferase HP1γ-S...
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| Veröffentlicht in: | Nat Struct Mol Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227600/ https://ncbi.nlm.nih.gov/pubmed/24413057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2746 |
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