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NF-κB– and AP-1–Mediated DNA Looping Regulates Osteopontin Transcription in Endotoxin-Stimulated Murine Macrophages

Osteopontin (OPN) is expressed by various immune cells and modulates both innate and adaptive immune responses. However, the molecular mechanisms that control opn gene expression, especially at the chromatin level, remain largely unknown. We have previously demonstrated many specific cis- and trans-...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Zhao, Wei, Wang, Lijuan, Zhang, Meng, Wang, Peng, Zhang, Lei, Yuan, Chao, Qi, Jianni, Qiao, Yu, Kuo, Paul C., Gao, Chengjiang
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227538/
https://ncbi.nlm.nih.gov/pubmed/21257959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003626
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