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Differential Expression of Intracellular and Secreted Osteopontin Isoforms by Murine Macrophages in Response to Toll-like Receptor Agonists

Osteopontin (OPN), expressed by various immune cells, modulates both innate and adaptive immune responses. Different immune cells have shown differential expression of the two isoforms of OPN: secreted form of OPN (sOPN) and intracellular form of OPN (iOPN). However, the molecular mechanisms that co...

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Autors principals: Zhao, Wei, Wang, Lijuan, Zhang, Lei, Yuan, Chao, Kuo, Paul C., Gao, Chengjiang
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2898311/
https://ncbi.nlm.nih.gov/pubmed/20427276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.110312
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