PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPS

Lipopolysaccharide (LPS) is a bacterial wall endotoxin producing many pathophysiological conditions including myocardial inflammation leading to cardiotoxicity. Epoxyeicosatrienoic acids (EETs) are biologically active metabolites of arachidonic acids capable of activating protective cellular pathway...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Samokhvalov, Victor, Vriend, Jelle, Jamieson, Kristi L., Akhnokh, Maria K., Manne, Rajkumar, Falck, John R., Seubert, John M.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2014
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227494/
https://ncbi.nlm.nih.gov/pubmed/25426073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00242
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